Mr. Andrew is a one binome on the crew of the Saucy Mare under The Crimson Binome. He is the ship's engineer. Mr. Andrew has a moustache and a patch over his one eye that he raises up in order to see.
Mr. Andrew and the Saucy Mare first visited Mainframe when they it raided the city for software. He helped Miss Sally steal Glitch from Bob without his knowledge, a great feat to take a Key Tool from a Guardian. Both of them received a 2,000 unit bonus for taking Glitch. The Saucy Mare tried to escape the system but Dot Matrix convinced Captain Capacitor that commerce was more profitable then piracy. They became partners in intersystem commerce. (The Crimson Binome)
After Mainframe was cut off from the Net the Saucy Mare tried to open up trade in other systems but ended up in trouble. Mr. Andrew and most of the crew was arrested and the Saucy Mare was impounded in the Desert Port Systems harbour. With the help of Matrix and AndrAIa, Captain Capacitor freed Mr. Andrew and his crew, and then retook the Mare. On their way out of the system, the ship was damaged by weapon fire. They managed to get out of the system but Mr. Andrew had to inform Captain Capacitor that the engines were severely damaged and the portal generator was off-line. (The Return of The Crimson Binome)
They quickly went to the Edge of Beyond in order to enter the Web and search for Bob. Ray Tracer helped them stabilize the tear into a portal. The crew covered the Mare in dead Web Creatures to protect it from the Web and Ray Tracer stabilized the Tear so that they could enter the Web. (The Edge of Beyond)
The ship ended up in a battle with the Web Riders. Mr. Andrew was indispensable in fighting the Riders. They nearly lost until Bob arrived calling off the battle. The Saucy Mare transported everyone to the Web Address of Mainframe, once there it encountered traps laid by Mouse, each one worse than the last. The Saucy Mare was almost destroyed but Bob merged with Glitch and stabilized the tear, opening the way to Mainframe. (Mousetrap)
After the Viral Wars, Mainframe began to crash. As the city collapsed, Mr. Andrew and the crew of the Saucy Mare were seen in the Principal Office sharing a drink with Old Man Pearson, Binky, Algernon, and Mr. Mitchell. (End Prog)